Likewise, you should avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of hydrocodone. If you are taking certain long-acting formulations of hydrocodone, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment.
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Switch to professional interaction data Drug and food interactionsĭo not use alcohol or medications that contain alcohol while you are receiving treatment with HYDROcodone. Do not stop using any medications without first talking to your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Also, because these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination, you should avoid driving or operating hazardous machinery until you know how they affect you. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications.
Talk to your doctor if you have any questions or concerns. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death.
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